Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 2/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 8/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.46 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15323484 | 0.91 | FDPS (0.56) | LPAR3SMPD1GGPS1FDPSLPAR1 | |
| SCHEMBL627026 | 0.89 | FDPS (0.55) | LPAR3SMPD1GGPS1FDPSLPAR1 | |
| SCHEMBL3792251 | 0.78 | FAAH (0.54) | LPAR3LPAR1LPAR2LPAR4ENPP2 | |
| SCHEMBL1367614 | 0.78 | FAAH (0.54) | LPAR3LPAR1LPAR2LPAR4ENPP2 | |
| SCHEMBL7078962 | 0.76 | GGPS1 (0.51) | LPAR3SMPD1GGPS1FDPSS1PR4 | |
| SCHEMBL2131483 | 0.75 | GGPS1 (0.48) | SMPD1GGPS1FDPSS1PR4S1PR1 | |
| Phosphoric Acid SCHEMBL11225058 | 0.74 | LPAR3 (0.64) | LPAR3GGPS1LPAR1LPAR2TRPV1 | |
| Phosphoric Acid SCHEMBL3911255 | 0.74 | LPAR3 (0.64) | LPAR3GGPS1LPAR1LPAR2TRPV1 | |
| SCHEMBL7551569 | 0.74 | FDPS (0.53) | LPAR3SMPD1GGPS1FDPSMEN1 | |
| SCHEMBL9494558 | 0.74 | FAAH (0.44) | ALDH1A1TRPV1MEN1FAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050112661-A1 | Methods for delivering nucleic acid molecules into cells and assessment thereof | GLAXO GROUP LIMITED (GB) | 2005-05-26 | — | — | US | disclosed |
| US-20030186390-A1 | Methods for delivering nucleic acid molecules into cells and assessment thereof | CHROMOS MOLECULAR SYSTEMS, INC (CA) | 2003-10-02 | — | — | US | disclosed |
| US-20030059940-A1 | Methods for delivering nucleic acid molecules into cells and assessment thereof | GLAXO GROUP LIMITED (GB) | 2003-03-27 | — | — | US | disclosed |
| US-20030003435-A1 | Methods for delivering nucleic acid molecules into cells and assessment thereof | CHROMOS MOLECULAR SYSTEMS, INC. | 2003-01-02 | — | — | US | disclosed |