Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.73 |
| ▸ | HTR2B | P41595 | 3/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | GID4 | Q8IVV7 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508988 | 0.90 | HTR2C (0.73) | HTR2CHTR2BHDAC1HDAC3HDAC2 | |
| SCHEMBL6511035 | 0.90 | HTR2C (0.73) | HTR2CHTR2BHDAC1HDAC3HDAC2 | |
| SCHEMBL6507511 | 0.87 | HTR2C (0.77) | HTR2CHTR2BHDAC1HDAC3HDAC2 | |
| SCHEMBL6508031 | 0.85 | HTR2C (0.77) | HTR2CHTR2BHDAC1HDAC3HDAC2 | |
| SCHEMBL6510239 | 0.85 | HTR2C (0.77) | HTR2CHTR2BHDAC1HDAC3HDAC2 | |
| SCHEMBL20111165 | 0.85 | HTR2C (1.00) | HTR2CHTR2BHDAC1HDAC3HDAC2 | |
| Hydrochloric Acid SCHEMBL30001584 | 0.84 | HTR2C (0.76) | HTR2CHTR2BHDAC1HDAC3HDAC2 | |
| SCHEMBL6510388 | 0.84 | HTR2C (0.72) | HTR2CHTR2BHDAC1HDAC3HDAC2 | |
| SCHEMBL6510385 | 0.83 | HTR2C (0.73) | HTR2CHTR2BHDAC1HDAC3HDAC2 | |
| SCHEMBL15833076 | 0.83 | HTR2C (0.61) | HTR2CHTR2BHDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040108-A1 | PROLINAMIDE DERIVATIVES AS SODIUM AND/OR CALCIUM CHANNEL BLOCKERS OR SELECTIVE MAO-B INHIBITORS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-05-06 | — | — | WO | claimed |
| WO-2005040108-A1 | PROLINAMIDE DERIVATIVES AS SODIUM AND/OR CALCIUM CHANNEL BLOCKERS OR SELECTIVE MAO-B INHIBITORS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-05-06 | — | — | WO | disclosed |