SCHEMBL6511016

SCHEMBL6511016

CC(C)C(=O)C(C)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 6/20 0.71
CYP1A2 P05177 1/20 0.46
GAA P10253 1/20 0.46
CYP2C9 P11712 1/20 0.46
PKM P14618 1/20 0.46
CYP2C19 P33261 1/20 0.46
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
ACP3 P15309 2/20 0.46
MAPT P10636 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 1/20 0.44
FABP2 P12104 1/20 0.44
TSHR P16473 1/20 0.44
AKR1C4 P17516 1/20 0.44
ADRA2B P18089 1/20 0.44
CHRM3 P20309 1/20 0.44
PTGS1 P23219 1/20 0.44
HTR2C P28335 1/20 0.44
DRD3 P35462 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10120043 0.87 PTGS2 (0.52) PTGS2MAPTSMN1; SMN2PTGS1HTR2C
SCHEMBL10139331 0.87 PTGS2 (0.52) PTGS2MAPTSMN1; SMN2PTGS1HTR2C
SCHEMBL9911551 0.87 PTGS2 (0.52) PTGS2MAPTSMN1; SMN2PTGS1HTR2C
SCHEMBL1211557 0.83 PTGS2 (1.00) PTGS2CYP1A2CYP2C9CYP2C19MAPT
SCHEMBL7826539 0.83 PTGS2 (1.00) PTGS2CYP1A2CYP2C9CYP2C19MAPT
SCHEMBL17524311 0.82 PTGS2 (0.81) PTGS2CYP1A2GAACYP2C9PKM
Hydrochloric Acid SCHEMBL5753890 0.82 PTGS2 (0.96) PTGS2CYP1A2CYP2C9CYP2C19MAPT
SCHEMBL13385661 0.81 PTGS2 (0.56) PTGS2CYP1A2GAACYP2C9PKM
SCHEMBL8696877 0.80 PTGS2 (0.71) PTGS2CYP1A2GAACYP2C9PKM
SCHEMBL11738135 0.80 PTGS2 (0.71) PTGS2CYP1A2GAACYP2C9PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6867310-B1 Arylation and vinylation of activated carbons MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-03-15 US disclosed