Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 19/20 | 0.80 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.78 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.59 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8282112 | 0.89 | OXTR (1.00) | OXTRAVPR1AAVPR2 | |
| SCHEMBL6510715 | 0.87 | OXTR (0.87) | OXTRAVPR1AAVPR2TUBB4ATUBB | |
| SCHEMBL8282084 | 0.77 | OXTR (0.81) | OXTRAVPR1AAVPR2 | |
| SCHEMBL8281669 | 0.76 | OXTR (0.77) | OXTRAVPR1AAVPR2 | |
| SCHEMBL8281027 | 0.76 | OXTR (1.00) | OXTRAVPR1AAVPR2 | |
| SCHEMBL17367287 | 0.76 | OXTR (0.69) | OXTRAVPR1AAVPR2 | |
| SCHEMBL8280934 | 0.75 | OXTR (0.81) | OXTRAVPR1AAVPR2 | |
| SCHEMBL8279809 | 0.75 | OXTR (0.68) | OXTRAVPR1AAVPR2 | |
| SCHEMBL8282609 | 0.74 | OXTR (1.00) | OXTRAVPR1AAVPR2 | |
| SCHEMBL15840847 | 0.74 | OXTR (0.60) | OXTRAVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082866-A2 | SUBSTITUTED 1, 2, 4- TRIAZOLE DERIVATIVES AS OXYTOCIN ANTAGONISTS | PFIZER LIMITED (GB) | 2005-09-09 | — | — | WO | disclosed |
| WO-2005082866-A2 | SUBSTITUTED 1, 2, 4- TRIAZOLE DERIVATIVES AS OXYTOCIN ANTAGONISTS | PFIZER LIMITED (GB) | 2005-09-09 | — | — | WO | disclosed |