SCHEMBL6511271

SCHEMBL6511271

C#Cc1ccc(C(=O)Sc2ccccn2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
ALDH1A1 P00352 9/20 0.40
NPC1 O15118 7/20 0.40
RAB9A P51151 7/20 0.40
HPGD P15428 5/20 0.40
SMN1; SMN2 Q16637 5/20 0.40
HSD17B10 Q99714 3/20 0.40
KDM4E B2RXH2 2/20 0.40
ALOX15 P16050 1/20 0.40
MAPT P10636 5/20 0.39
KMT2A Q03164 3/20 0.39
EHMT2 Q96KQ7 1/20 0.39
EHMT1 Q9H9B1 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
MEN1 O00255 2/20 0.36
PKM P14618 1/20 0.36
LMNA P02545 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3822586 0.85 CA1 (0.46) POLBALDH1A1NPC1RAB9AHPGD
SCHEMBL4483430 0.82 ALDH1A1 (0.54) POLBALDH1A1NPC1RAB9AHPGD
SCHEMBL10126446 0.81 POLB (0.45) POLBALDH1A1NPC1RAB9AHPGD
SCHEMBL3024916 0.80 NPC1 (0.61) POLBALDH1A1NPC1RAB9AHPGD
SCHEMBL6937212 0.80 TLR7 (0.49) POLBALDH1A1NPC1RAB9AHPGD
SCHEMBL5089864 0.79 KMT2A (0.46) POLBALDH1A1NPC1RAB9AHPGD
SCHEMBL6420708 0.76 MAPT (0.59) POLBALDH1A1NPC1RAB9AHPGD
SCHEMBL2259597 0.76 POLB (0.55) POLBALDH1A1NPC1RAB9AHPGD
SCHEMBL17662589 0.76 NPC1 (0.45) POLBALDH1A1NPC1RAB9AHPGD
SCHEMBL16629710 0.76 ALDH1A1 (0.43) POLBALDH1A1NPC1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916982-B2 Synthesis of perylene-porphyrin building blocks and polymers thereof for the production of light-harvesting arrays NORTH CAROLINA STATE UNIVERSITY (US) 2005-07-12 US disclosed
WO-2003105237-A1 SYNTHESIS OF PERYLENE-PORPHYRIN BUILDING BLOCKS AND POLYMERS THEREOF FOR THE PRODUCTION OF LIGHT-HARVESTING ARRAYS NORTH CAROLINA STATE UNIVERSITY (US) 2003-12-18 WO disclosed
US-20030075216-A1 Synthesis of perylene-porphyrin building blocks and polymers thereof for the production of light-harvesting arrays NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-04-24 US disclosed