Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483430 | 0.86 | ALDH1A1 (0.54) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10126446 | 0.85 | POLB (0.45) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6937212 | 0.83 | TLR7 (0.49) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5089864 | 0.83 | KMT2A (0.46) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2259597 | 0.83 | POLB (0.55) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL17662589 | 0.83 | NPC1 (0.45) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6420708 | 0.83 | MAPT (0.59) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3822586 | 0.80 | CA1 (0.46) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6511271 | 0.80 | POLB (0.41) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL16629710 | 0.80 | ALDH1A1 (0.43) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9417245-B2 | Porphyrinic compounds for use in flow cytometry | NORTH CAROLINA STATE UNIVERSITY (US) | 2016-08-16 | — | — | US | disclosed |
| US-9417245-B2 | Porphyrinic compounds for use in flow cytometry | NORTH CAROLINA STATE UNIVERSITY (US) | 2016-08-16 | — | — | US | disclosed |
| US-20150153350-A1 | PORPHYRINIC COMPOUNDS FOR USE IN FLOW CYTOMETRY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-06-04 | — | — | US | disclosed |
| US-20150153350-A1 | PORPHYRINIC COMPOUNDS FOR USE IN FLOW CYTOMETRY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-06-04 | — | — | US | disclosed |
| US-8980565-B2 | Porphyrinic compounds for use in flow cytometry | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-03-17 | — | — | US | disclosed |
| US-8980565-B2 | Porphyrinic compounds for use in flow cytometry | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-03-17 | — | — | US | disclosed |
| US-8546088-B2 | Porphyrinic compounds for use in flow cytometry | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-10-01 | — | — | US | disclosed |
| US-8546088-B2 | Porphyrinic compounds for use in flow cytometry | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-10-01 | — | — | US | disclosed |
| US-8445695-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-05-21 | — | — | US | disclosed |
| US-8420804-B2 | Formyl- and acetal-porphyrins bearing tripodal linking groups | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-04-16 | — | — | US | disclosed |
| US-7153975-B2 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2006-12-26 | — | — | US | disclosed |
| US-20050282778-A1 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-12-22 | — | — | US | disclosed |
| US-20050282779-A1 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-12-22 | — | — | US | disclosed |
| US-6946552-B2 | Refined routes to chlorin building blocks | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-09-20 | — | — | US | disclosed |
| US-20050165228-A1 | Refined routes to chlorin building blocks | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-07-28 | — | — | US | disclosed |
| US-6728129-B2 | Multistate triple-decker dyads in three distinct architectures for information storage applications | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-04-27 | — | — | US | disclosed |
| US-20030169618-A1 | Multistate triple-decker dyads in three distinct architectures for information storage applications | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER | 2003-09-11 | — | — | US | disclosed |
| WO-2003071552-A1 | MULTISTATE TRIPLE-DECKER DYADS IN THREE DISTINCT ARCHITECTURES FOR INFORMATION STORAGE APPLICATIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-08-28 | — | — | WO | disclosed |
| US-20030096989-A1 | Refined routes to chlorin building blocks | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-05-22 | — | — | US | disclosed |
| WO-2002092601-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282778-A1 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | DECR2, ANTXR2, CD79B | NPC1 3425/4885RAB9A 2735/4885ALDH1A1 2207/4885 |
| US-20050282779-A1 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | DECR2, ANTXR2, CD79B | NPC1 3425/4885RAB9A 2735/4885ALDH1A1 2207/4885 |
| US-20050165228-A1 | Refined routes to chlorin building blocks | DHFR, DDT, SHARPIN | NPC1 3982/4885RAB9A 4284/4885ALDH1A1 3657/4885 |
| US-20030096989-A1 | Refined routes to chlorin building blocks | DHFR, DDT, SHARPIN | NPC1 3982/4885RAB9A 4284/4885ALDH1A1 3657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.