Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 7/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2002781 | 0.87 | KDM4E (0.58) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL5300204 | 0.86 | KDM4E (0.54) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8420669 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6511279 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL31401447 | 0.81 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL22226387 | 0.80 | CA2 (0.52) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL7360846 | 0.80 | KDM4E (0.64) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL27947356 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8102330 | 0.78 | HPGD (0.60) | ALDH1A1MAPTHPGDLMNANPSR1 | |
| SCHEMBL17080270 | 0.77 | ALDH1A1 (0.62) | KDM4EALDH1A1MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031572-A1 | PYRIDYLPYRROLE DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-30 | — | — | EP | disclosed |