Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.71 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5041898 | 0.89 | ADRB2 (0.89) | ADRB2CHRM3 | |
| SCHEMBL5041896 | 0.89 | ADRB2 (0.89) | ADRB2CHRM3 | |
| SCHEMBL6509816 | 0.88 | ADRB2 (0.80) | ADRB2CHRM3 | |
| SCHEMBL6507981 | 0.85 | ADRB2 (0.64) | ADRB2CHRM3 | |
| SCHEMBL6505181 | 0.85 | ADRB2 (0.64) | ADRB2CHRM3 | |
| SCHEMBL3914499 | 0.85 | ADRB2 (0.66) | ADRB2ERCC1ERCC4CHRM3LMNA | |
| SCHEMBL13840726 | 0.85 | ADRB2 (0.66) | ADRB2ERCC1ERCC4CHRM3LMNA | |
| SCHEMBL6509832 | 0.84 | ADRB2 (0.71) | ADRB2CHRM3 | |
| SCHEMBL6507640 | 0.84 | ADRB2 (0.69) | ADRB2CHRM3 | |
| SCHEMBL5998102 | 0.84 | ADRB2 (0.90) | ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092841-A1 | COMPOUNDS HAVING BETA-AGONIST ACTIVITY | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |