Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | SDHA | P31040 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CALML3 | P27482 | 1/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511851 | 1.00 | MAOA (0.53) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6515812 | 0.91 | MAOA (0.51) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6515817 | 0.91 | MAOA (0.51) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6520209 | 0.88 | MAOA (0.51) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6520202 | 0.88 | MAOA (0.51) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6515809 | 0.84 | MAOA (0.49) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6514783 | 0.84 | F10 (0.42) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6515814 | 0.84 | MAOA (0.49) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6514786 | 0.84 | F10 (0.42) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6514585 | 0.83 | MAOA (0.52) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082900-A2 | OXAZOLIDINONE AMIDOXIMES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |