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SCHEMBL6520202

SCHEMBL6520202

CON=c1oc2cc(N3C[C@H](CNC(C)=O)OC3=O)ccc2n1C(C)C

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 5/20 0.51
▸ MAOB P27338 3/20 0.51
▸ PTGS1 P23219 2/20 0.51
▸ SDHA P31040 2/20 0.51
▸ LMNA P02545 1/20 0.51
▸ CALML3 P27482 1/20 0.51
▸ ABCB11 O95342 1/20 0.42
▸ F10 P00742 3/20 0.42
▸ TOP2B Q02880 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6520209 1.00 MAOA (0.51) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6511851 0.88 MAOA (0.53) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6511847 0.88 MAOA (0.53) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6515817 0.88 MAOA (0.51) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6515812 0.88 MAOA (0.51) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6509785 0.83 MAOA (0.51) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6509786 0.83 MAOA (0.51) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6510940 0.80 MAOA (0.53) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6510933 0.80 MAOA (0.53) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6515809 0.80 MAOA (0.49) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005082900-A2 OXAZOLIDINONE AMIDOXIMES AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2005-09-09 — — WO disclosed