Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 9/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81976 | 0.94 | IDO1 (0.45) | IDO1DAOTACR1CES2SIRT2 | |
| SCHEMBL2393670 | 0.85 | IDO1 (0.48) | IDO1DAOTACR1CES2TAAR1 | |
| SCHEMBL7384474 | 0.80 | TAAR1 (0.59) | IDO1DAOTAAR1HDAC1HDAC8 | |
| SCHEMBL16298283 | 0.80 | TAAR1 (0.59) | IDO1DAOTAAR1HDAC1HDAC8 | |
| SCHEMBL5781780 | 0.79 | TAAR1 (0.55) | IDO1SIRT2TAAR1HDAC1HDAC8 | |
| SCHEMBL7574477 | 0.79 | RAD52 (0.49) | IDO1DAOTACR1TAAR1 | |
| SCHEMBL14402519 | 0.79 | PTGS2 (0.50) | IDO1DAOTACR1 | |
| SCHEMBL7777598 | 0.78 | RAD52 (0.48) | IDO1DAOTACR1TAAR1 | |
| SCHEMBL28703223 | 0.78 | RAD52 (0.48) | IDO1DAOTACR1TAAR1 | |
| SCHEMBL6231341 | 0.78 | RAD52 (0.48) | IDO1DAOTACR1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | disclosed |