Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.57 |
| ▸ | TUBB | P07437 | 1/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1437123 | 0.86 | SLC22A6 (0.68) | HDAC6HDAC8HDAC1SMPD1CA1 | |
| SCHEMBL19519009 | 0.86 | PDE4D (0.60) | PDE4DTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1436474 | 0.85 | SMPD1 (0.66) | HDAC6HDAC8HDAC1SMPD1CA1 | |
| SCHEMBL4162113 | 0.84 | PDE4D (0.58) | PDE4DTUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL28155688 | 0.84 | SLC22A6 (0.66) | HDAC6HDAC8HDAC1SMPD1CA1 | |
| Hydrochloric Acid SCHEMBL9638760 | 0.84 | SMPD1 (0.64) | HDAC6HDAC8HDAC1SMPD1CA1 | |
| Hydrochloric Acid SCHEMBL3566445 | 0.83 | PDE4D (0.57) | PDE4DTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14880182 | 0.82 | TAS1R3 (0.60) | HDAC6HDAC8HDAC1SMPD1CA1 | |
| Isovanillic Acid Methyl Ester SCHEMBL29497236 | 0.81 | CA1 (0.69) | PDE4DTUBB4ATUBBTUBA3CTUBA1B | |
| Isovanillic Acid Methyl Ester SCHEMBL57367 | 0.81 | CA1 (0.69) | PDE4DTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050181464-A1 | Novel purified polypeptides from bacteria | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2005-08-18 | — | — | US | disclosed |
| WO-2003102190-A2 | BACTERIAL POLYPEPTIDES INVOLVED IN VIABILITY | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2003-12-11 | — | — | WO | disclosed |