Isovanillic Acid Methyl Ester

Isovanillic Acid Methyl Ester

SCHEMBL57367

COC(=O)c1ccc(OC)c(O)c1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.69
CA2 P00918 3/20 0.69
XDH P47989 2/20 0.69
CA12 O43570 2/20 0.69
CA7 P43166 2/20 0.69
CA9 Q16790 2/20 0.69
CA14 Q9ULX7 2/20 0.69
MAPT P10636 3/20 0.64
P4HB P07237 1/20 0.63
TUBB4A P04350 2/20 0.60
TUBB P07437 2/20 0.60
TUBA3C P0DPH7 2/20 0.60
TUBA1B P68363 2/20 0.60
TUBA4A P68366 2/20 0.60
TUBB4B P68371 2/20 0.60
TUBB3 Q13509 2/20 0.60
TUBB2A Q13885 2/20 0.60
TUBB8 Q3ZCM7 2/20 0.60
TUBA3E Q6PEY2 2/20 0.60
TUBA1A Q71U36 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isovanillic Acid Methyl Ester SCHEMBL29497236 1.00 CA1 (0.69) CA1CA2XDHCA12CA7
SCHEMBL10422069 0.89 P4HB (0.64) CA1CA2XDHCA12CA7
SCHEMBL24287563 0.85 TUBB4A (0.57) CA1CA2XDHCA12CA7
Methyl Vanillate SCHEMBL275939 0.85 KMT2A (0.72) CA1CA2XDHCA12CA7
Methyl Vanillate SCHEMBL25417789 0.85 KMT2A (0.72) CA1CA2XDHCA12CA7
Methyl Vanillate SCHEMBL31157843 0.85 KMT2A (0.72) CA1CA2XDHCA12CA7
Methyl Vanillate SCHEMBL29640509 0.85 KMT2A (0.72) CA1CA2XDHCA12CA7
Veratric Acid Methyl Ester SCHEMBL2050732 0.84 MAPT (0.86) CA1CA2XDHCA12CA7
Veratric Acid Methyl Ester SCHEMBL29573244 0.84 MAPT (0.86) CA1CA2XDHCA12CA7
SCHEMBL27575811 0.84 TUBB4A (0.80) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103524433-A Method for synthesizing gefitinib and intermediate thereof TIANJIN PHARMACN MEDICAL TECHNOLOGY CO LTD 2014-01-22 CN claimed
CN-103304491-A Preparation method of gefitinib LIANYUNGANG SHENGHE BIOTECHNOLOGY CO LTD 2013-09-18 CN claimed
CN-101148439-B Preparing method for gefitinib UNIV SOUTHEAST 2011-06-22 CN claimed
CN-101148439-A Preparing method for gefitinib UNIV SOUTHEAST (CN) 2008-03-26 CN claimed
EP-1144408-A1 SUBSTITUTED 1-(PIERIDIN-4-YL)-3-(ARYL) ISOTHIOUREAS THEIR PREPARATION AND THERAPEUTIC APPLICATION PIERRE FABRE MEDICAMENT (FR) 2001-10-17 EP claimed
WO-2000043391-A1 SUBSTITUTED 1-(PIERIDIN-4-YL)-3-(ARYL) ISOTHIOUREAS THEIR PREPARATION AND THERAPEUTIC APPLICATION PIERRE FABRE MEDICAMENT (FR) 2000-07-27 WO claimed
US-20260108497-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICALC., LTD. (JP) 2026-04-23 US disclosed
US-12509470-B2 Antiviral heterocyclic compounds ENANTA PHARMACEUTICALS, INC. (US) 2025-12-30 US disclosed
EP-2603098-B1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER FIRMENICH INCORPORATED (US) 2025-08-06 EP disclosed
US-20250179000-A1 METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF Sanford Burnham Prebys Medical Discovery Institute 2025-06-05 US disclosed
US-20250073236-A1 PYRIMIDINE COMPOUNDS CONTAINING ACIDIC GROUPS APROS THERAPEUTICS INC (US) 2025-03-06 US disclosed
CN-113563244-B Substituted aza five-membered ring compound and application thereof in medicine 广东东阳光药业股份有限公司 2025-01-10 CN disclosed
CN-113302184-B 1,3, 4-Oxadiazolinone compounds and medicaments 日本新药株式会社 2024-11-22 CN disclosed
WO-1994010258-A1 CHEMILUMINESCENT ELECTRON-RICH ARYL-SUBSTITUTED 1,2-DIOXETANES ABBOTT LABORATORIES (US) 1994-05-11 WO disclosed
WO-1994002465-A1 INHIBITORS OF c-AMP PHOSPHODIESTERASE AND TNF RHONE-POULENC RORER LIMITED (GB) 1994-02-03 WO disclosed
US-5208247-A Antianaphylactic agents or septic shock AMERICAN CYANAMID COMPANY (US) 1993-05-04 US disclosed
EP-0530444-A1 Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor AMERICAN CYANAMID COMPANY (US) 1993-03-10 EP disclosed
CN-1069025-A The aryl of platelet activating factor, acid amides, imide and carbamate pyridine antagonists AMERICAN CYANAMID CO (US) 1993-02-17 CN disclosed
US-5059610-A QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1991-10-22 US disclosed
US-4920132-A Quinoline derivatives and use thereof as antagonists of leukotriene D4 RORER PHARMACEUTICAL CORP. (US) 1990-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509470-B2 Antiviral heterocyclic compounds NR3C1, ZC3HAV1, HAVCR2 CA1 2525/4885CA2 1633/4885XDH 620/4885
US-20260108497-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION PDE7B, PDE4B, PDE1B CA1 1395/4885CA2 270/4885XDH 100/4885
US-20250179000-A1 METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF GRM3, GRM2, GRM1 CA1 1732/4885CA2 990/4885XDH 3856/4885
US-20250073236-A1 PYRIMIDINE COMPOUNDS CONTAINING ACIDIC GROUPS MAVS, TLR7, STING1 CA1 4696/4885CA2 4262/4885XDH 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.