SCHEMBL6511952

SCHEMBL6511952

Fc1ccc([C@@]2(CCl)O[C@@H]2c2ccccc2Cl)cc1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.40
P2RX7 Q99572 2/20 0.33
NPY5R Q15761 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32
MEN1 O00255 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6508783 0.87 KCNN4 (0.42) KCNN4NPY5RHTR2AHTR2CHTR2B
SCHEMBL6503437 0.87 KCNN4 (0.40) KCNN4P2RX7NPY5RHTR2AHTR2C
SCHEMBL6504421 0.87 KCNN4 (0.42) KCNN4NPY5RHTR2AHTR2CHTR2B
SCHEMBL6409586 0.87 KCNN4 (0.42) KCNN4NPY5RHTR2AHTR2CHTR2B
SCHEMBL1498863 0.87 P2RX7 (0.35) KCNN4P2RX7HTR2AHTR2CHTR2B
SCHEMBL2291071 0.85 P2RX7 (0.41) KCNN4P2RX7HTR2AHTR2CHTR2B
SCHEMBL3660507 0.85 ALDH1A1 (0.32) KCNN4P2RX7HTR2AHTR2CHTR2B
SCHEMBL1498913 0.83 P2RX7 (0.32) KCNN4P2RX7HTR2AHTR2CHTR2B
SCHEMBL3661654 0.81 HTR2A (0.33) KCNN4P2RX7HTR2AHTR2CHTR2B
SCHEMBL1498964 0.81 PSEN1 (0.35) KCNN4P2RX7HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005056548-A1 ENANTIOMERICALLY PURE EPOXICONAZOLE AND ITS USE AS CROP PROTECTION AGENT CHEMINOVA A/S (DK) 2005-06-23 WO disclosed