Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3423921 | 0.83 | KMT2A (0.46) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL889833 | 0.83 | KMT2A (0.46) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL6512316 | 0.80 | KMT2A (0.37) | KMT2ATLR2MDM2HDAC3HDAC4 | |
| SCHEMBL20371116 | 0.78 | KMT2A (0.44) | KMT2AMDM2MDM4TP53 | |
| SCHEMBL8843737 | 0.78 | KMT2A (0.52) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL19402725 | 0.78 | MDM2 (0.59) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL29379713 | 0.78 | MDM2 (0.59) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL29470876 | 0.78 | MDM2 (0.59) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL13402819 | 0.78 | MDM2 (0.59) | KMT2ATLR2MDM2MDM4TP53 | |
| SCHEMBL29414971 | 0.78 | MDM2 (0.59) | KMT2ATLR2MDM2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050233360-A1 | Nucleic acid probes and methods to detect and/or quantify nucleic acid analytes | PROLIGO, LLC (US) | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050233360-A1 | Nucleic acid probes and methods to detect and/or quantify nucleic acid analytes | HLA-C, HLA-B, SLC43A3 | KMT2A 3685/4885TLR2 1565/4885MDM2 1395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.