Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.49 |
| ▸ | PPARG | P37231 | 6/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509616 | 0.98 | PPARA (0.49) | PPARAPPARGGRM2FBP1PPARD | |
| SCHEMBL6512591 | 0.92 | PPARA (0.41) | PPARAPPARGFBP1PPARD | |
| SCHEMBL6509466 | 0.91 | PPARA (0.41) | PPARAPPARGFBP1PPARD | |
| SCHEMBL6511438 | 0.90 | PPARA (0.60) | PPARAPPARGGRM2PPARDTLR7 | |
| SCHEMBL6512166 | 0.90 | PPARA (0.60) | PPARAPPARGGRM2PPARDTLR7 | |
| SCHEMBL6513058 | 0.90 | PPARA (0.60) | PPARAPPARGGRM2PPARDTLR7 | |
| SCHEMBL6511690 | 0.85 | PPARA (0.45) | PPARAPPARGPPARD | |
| SCHEMBL6512822 | 0.85 | PPARA (0.45) | PPARAPPARGPPARD | |
| SCHEMBL3284217 | 0.84 | PPARA (0.40) | PPARAPPARGGRM2FBP1PPARD | |
| SCHEMBL6508370 | 0.84 | PPARA (0.67) | PPARAPPARGFBP1PPARDTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | claimed |