Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29674859 | 1.00 | TDP1 (0.48) | TDP1ALDH1A1TSHRPKMHSD17B10 | |
| SCHEMBL13199105 | 0.93 | TDP1 (0.48) | TDP1ALDH1A1TSHRPKMHSD17B10 | |
| SCHEMBL3816541 | 0.93 | TDP1 (0.48) | TDP1ALDH1A1TSHRPKMHSD17B10 | |
| SCHEMBL7592620 | 0.90 | TDP1 (0.50) | TDP1ALDH1A1TSHRPKMHSD17B10 | |
| SCHEMBL15957606 | 0.90 | TDP1 (0.50) | TDP1ALDH1A1TSHRPKMHSD17B10 | |
| SCHEMBL11041007 | 0.87 | TDP1 (0.48) | TDP1ALDH1A1TSHRPKMHSD17B10 | |
| SCHEMBL11641139 | 0.84 | TDP1 (0.38) | TDP1ALDH1A1TSHRPKMHSD17B10 | |
| SCHEMBL9514735 | 0.83 | PKM (0.42) | TDP1ALDH1A1TSHRPKMIMPDH2 | |
| SCHEMBL4927428 | 0.83 | TDP1 (0.50) | TDP1ALDH1A1TSHRPKMHSD17B10 | |
| SCHEMBL15357214 | 0.81 | CYP1A2 (0.47) | TDP1ALDH1A1TSHRPKMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050148643-A1 | Carbamate compositions and methods fo rmodulating the activity of the CHK1 enzyme | AGOURON PHARMACEUTICALS, INC. | 2005-07-07 | — | — | US | disclosed |
| US-4186003-A | Hybrid fix system incorporating photodegradable polymers | XEROX CORPORATION (US) | 1980-01-29 | — | — | US | disclosed |
| US-3986874-A | DRIOGRAPHIC IMAGING METHOD | XEROX CORPORATION (US) | 1976-10-19 | — | — | US | disclosed |
| US-3964907-A | Method for the preparation of relief printing masters | XEROX CORPORATION (US) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148643-A1 | Carbamate compositions and methods fo rmodulating the activity of the CHK1 enzyme | CHEK1, CHEK2, RAD1 | TDP1 39/4885ALDH1A1 2713/4885TSHR 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.