SCHEMBL9514735

SCHEMBL9514735

Cc1c(C)c([N+](=O)[O-])c(N)c([N+](=O)[O-])c1C

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.42
ALDH1A1 P00352 5/20 0.41
TDP1 Q9NUW8 3/20 0.41
IMPDH2 P12268 2/20 0.37
TSHR P16473 4/20 0.35
CYP3A4 P08684 3/20 0.35
HTT P42858 2/20 0.35
POLB P06746 1/20 0.35
RECQL P46063 1/20 0.34
MAPT P10636 1/20 0.34
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27391845 0.92 PKM (0.41) PKMALDH1A1TDP1IMPDH2TSHR
SCHEMBL8151295 0.90 PKM (0.42) PKMALDH1A1TDP1IMPDH2TSHR
SCHEMBL11040935 0.85 PKM (0.39) PKMALDH1A1TDP1IMPDH2TSHR
SCHEMBL29242779 0.84 PKM (0.42) PKMALDH1A1TDP1IMPDH2TSHR
SCHEMBL11040704 0.84 PKM (0.42) PKMALDH1A1TDP1TSHRCYP3A4
SCHEMBL3816541 0.83 TDP1 (0.48) PKMALDH1A1TDP1IMPDH2TSHR
SCHEMBL6512240 0.83 TDP1 (0.48) PKMALDH1A1TDP1IMPDH2TSHR
SCHEMBL29674859 0.83 TDP1 (0.48) PKMALDH1A1TDP1IMPDH2TSHR
SCHEMBL22288212 0.82 PKM (0.41) PKMALDH1A1TDP1IMPDH2TSHR
SCHEMBL8358007 0.80 PKM (0.39) PKMALDH1A1TDP1IMPDH2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5156166-A None JP disclosed