Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512250 | 0.87 | PTGDR2 (0.63) | PTGDR2AKR1B1 | |
| SCHEMBL3557583 | 0.83 | PTGDR2 (0.59) | PTGDR2AKR1B1NPSR1CA12CA1 | |
| SCHEMBL6509625 | 0.82 | PTGDR2 (0.53) | PTGDR2AKR1B1L3MBTL1NPSR1CA12 | |
| SCHEMBL6510974 | 0.79 | PTGDR2 (0.77) | PTGDR2AKR1B1 | |
| SCHEMBL6512064 | 0.79 | PTGDR2 (0.60) | PTGDR2AKR1B1MCL1 | |
| SCHEMBL3556759 | 0.78 | PTGDR2 (0.77) | PTGDR2AKR1B1CA12CA1CA2 | |
| SCHEMBL6512958 | 0.76 | PTGDR2 (0.55) | PTGDR2AKR1B1 | |
| SCHEMBL10386848 | 0.72 | KDM4E (0.51) | MAPTL3MBTL1NPSR1TSHRALDH1A1 | |
| SCHEMBL6509296 | 0.71 | PTGDR2 (0.41) | PTGDR2AKR1B1NPSR1CA12CA1 | |
| SCHEMBL1386058 | 0.69 | PTGDR2 (0.73) | PTGDR2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121141-A1 | PYRROLOPYRIDINE DERIVATIVES AND USE THEREOF FOR TREATING DISEASES MEDIATED BY PROSTAGLANDIN D2 (PGD2) | OXAGEN LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |