Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.69 |
| ▸ | USP14 | P54578 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509625 | 0.87 | PTGDR2 (0.53) | PTGDR2AKR1B1USP14 | |
| SCHEMBL1385122 | 0.84 | PTGDR2 (0.87) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1386979 | 0.82 | PTGDR2 (1.00) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1385757 | 0.81 | PTGDR2 (0.75) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL6512250 | 0.81 | PTGDR2 (0.63) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL6511562 | 0.80 | PTGDR2 (0.44) | PTGDR2AKR1B1USP14 | |
| SCHEMBL1788367 | 0.80 | PTGDR2 (1.00) | PTGDR2AKR1B1 | |
| SCHEMBL1384482 | 0.78 | PTGDR2 (0.75) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL6509712 | 0.76 | PTGDR2 (0.71) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1386058 | 0.76 | PTGDR2 (0.73) | PTGDR2AKR1B1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121141-A1 | PYRROLOPYRIDINE DERIVATIVES AND USE THEREOF FOR TREATING DISEASES MEDIATED BY PROSTAGLANDIN D2 (PGD2) | OXAGEN LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |