Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27595464 | 0.92 | DGAT1 (0.39) | DGAT1GAAHPGDBTKCHRM3 | |
| SCHEMBL6597535 | 0.82 | DGAT1 (0.42) | DGAT1GAAEPHX1HPGDBTK | |
| SCHEMBL27950403 | 0.81 | GAA (0.41) | DGAT1GAAEPHX1HPGDBTK | |
| SCHEMBL28077248 | 0.78 | DGAT1 (0.45) | DGAT1GAAEPHX1HPGDBTK | |
| SCHEMBL1372061 | 0.77 | DGAT1 (0.46) | DGAT1GAAEPHX1HPGDBTK | |
| SCHEMBL26605075 | 0.77 | DGAT1 (0.37) | DGAT1GAAEPHX1HPGDBTK | |
| SCHEMBL20635363 | 0.76 | DGAT1 (0.43) | DGAT1GAAEPHX1HPGDBTK | |
| SCHEMBL1414449 | 0.75 | EPHX1 (0.37) | DGAT1GAAEPHX1HPGDCHRM3 | |
| SCHEMBL8864771 | 0.74 | EPHX1 (0.36) | DGAT1GAAEPHX1HPGDCHRM3 | |
| SCHEMBL28843811 | 0.74 | DGAT1 (0.35) | DGAT1GAAEPHX1BTKCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005075426-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS; PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS THEREOF | GLENMARK PHARMACEUTICALS LTD. (US) | 2005-08-18 | — | — | WO | claimed |