SCHEMBL6512429

SCHEMBL6512429

C=C(C)C(=O)OCC[Si](C)(C)Cl

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
TSHR P16473 3/20 0.48
ALDH1A1 P00352 2/20 0.43
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL692374 0.89 TSHR (0.55) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL6510428 0.88 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL8962565 0.87 TSHR (0.58) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL674776 0.86 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL23321704 0.85 TSHR (0.61) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL23321719 0.85 TSHR (0.61) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL23322177 0.85 TSHR (0.61) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL23322075 0.85 TSHR (0.61) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL23321940 0.85 TSHR (0.61) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL23321624 0.85 TSHR (0.61) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420711-B2 Mono ethylenically unsaturated polymerizable group containing polycarbosiloxane monomers BAUSCH & LOMB INCORPORATED (US) 2013-04-16 US disclosed
US-8420711-B2 Mono ethylenically unsaturated polymerizable group containing polycarbosiloxane monomers BAUSCH & LOMB INCORPORATED (US) 2013-04-16 US disclosed
US-20110009519-A1 MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS SOLTA MEDICAL, INC. 2011-01-13 US disclosed
US-20050124747-A1 Coating composition for ink-jet recording medium and ink-jet recording medium DEUTSCHE BANK AG, NEW YORK BRANCH, AS COLLATERAL AGENT 2005-06-09 US disclosed
EP-1470928-A1 COATING COMPOSITION FOR INK-JET RECORDING MEDIUM AND INK-JET RECORDING MEDIUM Clariant International Ltd. (CH) 2004-10-27 EP disclosed
US-6344521-B1 LIVING POLYMERS FMC CORPORATION 2002-02-05 US disclosed
US-6271330-B1 POLYSILOXANES, TELECHELIC POLYMERS AND LIVING POLYMERS WITH FREE RADICAL CATALYST FMC CORPORATION 2001-08-07 US disclosed
EP-1114734-A1 RESIN COMPOSITION FOR INK-JET RECORDING SHEET AND RECORDING SHEET MADE WITH THE SAME DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2001-07-11 EP disclosed
EP-0989162-A1 THERMOPLASTIC RESIN COMPOSITION, WATER-BASED COMPOSITION, HEAT-SENSITIVE PRESSURE-SENSITIVE ADHESIVE, AND HEAT-SENSITIVE SHEET Daicel Chemical Industries, Ltd. (JP) 2000-03-29 EP disclosed
EP-0989168-A1 Water-based coating composition Daicel Chemical Industries, Ltd. (JP) 2000-03-29 EP disclosed
US-6031060-A INCLUDES PROTECTED, FUNCTIONALIZED SILICONE POLYMERS, SUCH AS MONO-FUNCTIONAL, HOMOTELECHELIC, HETEROTELECHELIC, MACROMONOMER, AND RADIAL POLYMERS FMC CORPORATION (US) 2000-02-29 US disclosed
US-6020430-A LIVING POLYMERS FMC CORPORATION (US) 2000-02-01 US disclosed
US-5554706-A LOW TEMPERATURE LIQUID CRYSTALS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-09-10 US disclosed
EP-0695770-A1 COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-02-07 EP disclosed