SCHEMBL651280

SCHEMBL651280

C=CC(=O)OC(CCCCC)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.46
THRA P10827 1/20 0.46
ALDH1A1 P00352 1/20 0.43
NAAA Q02083 2/20 0.40
POLB P06746 1/20 0.40
CNR2 P34972 1/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 1/20 0.39
TSHR P16473 2/20 0.39
HPGD P15428 1/20 0.39
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL342568 0.99 THRB (0.48) THRBTHRAALDH1A1NAAAPOLB
SCHEMBL4970630 0.99 THRB (0.48) THRBTHRAALDH1A1NAAAPOLB
SCHEMBL9402077 0.99 THRB (0.48) THRBTHRAALDH1A1NAAAPOLB
SCHEMBL8086548 0.99 THRB (0.48) THRBTHRAALDH1A1NAAAPOLB
SCHEMBL4595927 0.96 THRB (0.44) THRBTHRAPOLBCNR2TSHR
SCHEMBL28106146 0.91 THRB (0.44) THRBTHRAALDH1A1POLBSMN1; SMN2
SCHEMBL3171202 0.90 THRB (0.40) THRBTHRAPOLBPPARGPPARA
SCHEMBL6058920 0.86 THRB (0.42) THRBTHRAALDH1A1LMNATSHR
SCHEMBL8040143 0.84 THRB (0.44) THRBTHRAALDH1A1NPC1RAB9A
SCHEMBL10711250 0.83 HCAR2 (0.55) THRBTHRAALDH1A1NAAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4267708-B1 THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS INFINEUM INT LTD (GB) 2025-07-02 EP disclosed
US-12281203-B2 Thermally responsive brush polymers having a copolymer backbone and copolymer arms INFINEUM INTERNATIONAL LIMITED (GB) 2025-04-22 US disclosed
US-20240309155-A1 Thermally Responsive Brush Polymers Having a Copolymer Backbone and Copolymer Arms INFINEUM INTERNATIONAL LIMITED (GB) 2024-09-19 US disclosed
EP-4267708-A1 THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS Infineum International Limited (GB) 2023-11-01 EP disclosed
WO-2022136384-A1 THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS INFINEUM INTERNATIONAL LIMITED (GB) 2022-06-30 WO disclosed
US-10358552-B2 Impact-resistant molding material having an improved characteristics profile EVONIK RÖHM GMBH (DE) 2019-07-23 US disclosed
US-9988548-B2 PMMA provided with impact resistance and having improved optical properties EVONIK ROEHM GMBH (DE) 2018-06-05 US disclosed
US-20170298217-A1 IMPACT-RESISTANT MOLDING MATERIAL HAVING AN IMPROVED CHARACTERISTICS PROFILE EVONIK ROEHM GMBH (DE) 2017-10-19 US disclosed
US-20150376437-A1 PMMA PROVIDED WITH IMPACT RESISTANCE AND HAVING IMPROVED OPTICAL PROPERTIES EVONIK ROEHM GMBH (DE) 2015-12-31 US disclosed
US-8119734-B2 Process for preparing aqueous dispersions EVONIK ROEHM GMBH (DE) 2012-02-21 US disclosed
US-20110218291-A1 PROCESS FOR PREPARING AQUEOUS DISPERSIONS EVONIK ROEHM GMBH (DE) 2011-09-08 US disclosed
EP-2220179-A1 IMPROVED COLOR AND DURABILITY OF INK-JET INK SETS WITH ADDED LATEX Hewlett-Packard Development Company, L.P. (US) 2010-08-25 EP disclosed
WO-2009078830-A1 IMPROVED COLOR AND DURABILITY OF INK-JET INK SETS WITH ADDED LATEX HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2009-06-25 WO disclosed
US-20060052515-A1 Process for producing aqueou dispersions ROEHM GMBH & CO. KG (DE) 2006-03-09 US disclosed
US-5270397-A Three phase emulsion polymer ROHM GMBH (DE) 1993-12-14 US disclosed