Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.64 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.60 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6520351 | 0.81 | MGAM (0.67) | NPBWR1GAAMGAMSIMGAM2 | |
| SCHEMBL29695905 | 0.79 | NPC1 (1.00) | NPC1RAB9AALDH1A1KDM4EGPR55 | |
| SCHEMBL162191 | 0.79 | NPC1 (1.00) | NPC1RAB9AALDH1A1KDM4EGPR55 | |
| SCHEMBL30336425 | 0.79 | GUSB (0.68) | NPC1RAB9AALDH1A1KDM4EGPR55 | |
| SCHEMBL31679095 | 0.79 | GUSB (0.68) | NPC1RAB9AALDH1A1KDM4EGPR55 | |
| SCHEMBL2872555 | 0.79 | GUSB (0.68) | NPC1RAB9AALDH1A1KDM4EGPR55 | |
| SCHEMBL27331502 | 0.78 | NPC1 (0.78) | NPC1RAB9AALDH1A1KDM4EGPR55 | |
| Methane SCHEMBL6992410 | 0.78 | MMP2 (0.50) | NPC1RAB9AALDH1A1KDM4EGPR55 | |
| SCHEMBL29568028 | 0.77 | NPBWR1 (0.73) | NPC1RAB9AALDH1A1KDM4EGPR55 | |
| SCHEMBL3334644 | 0.77 | NPBWR1 (0.73) | NPC1RAB9AALDH1A1KDM4EGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239767-A1 | Intermolecular SNAr of the heterocycle-activated nitro and fluoro groups-application in the synthesis of polyazamacrocyclic ligands | NATIONAL SCIENCE FOUNDATION | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239767-A1 | Intermolecular SNAr of the heterocycle-activated nitro and fluoro groups-application in the synthesis of polyazamacrocyclic ligands | TECR, PAICS, DCXR | NPC1 1730/4885RAB9A 4184/4885ALDH1A1 1812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.