SCHEMBL6512943

SCHEMBL6512943

COC(CCO)OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RCE1 Q9Y256 1/20 0.49
HTT P42858 5/20 0.46
KMT2A Q03164 2/20 0.44
MAPT P10636 2/20 0.42
NPC1 O15118 1/20 0.42
SLC1A3 P43003 2/20 0.40
SLC1A2 P43004 2/20 0.40
SLC1A1 P43005 2/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
GAA P10253 1/20 0.37
RECQL P46063 1/20 0.37
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12694282 0.89 TSHR (0.44) RCE1KMT2ANPC1SLC1A3SLC1A2
SCHEMBL5566637 0.85 RCE1 (0.51) RCE1HTTKMT2AMAPTNPC1
SCHEMBL1056428 0.82 RCE1 (0.46) RCE1HTTKMT2AMAPTNPC1
SCHEMBL28246143 0.81 RCE1 (0.50) RCE1HTTKMT2AMAPTNPC1
SCHEMBL9615023 0.81 CYP4F2 (0.42) RCE1KMT2ASLC1A3SLC1A2SLC1A1
SCHEMBL7814719 0.81 RCE1 (0.44) RCE1HTTKMT2ANPC1ALDH1A1
SCHEMBL8843803 0.80 OPRK1 (0.50) RCE1HTTKMT2AMEN1CYP1A2
SCHEMBL21677653 0.79 RCE1 (0.49) RCE1HTTKMT2AMAPTNPC1
SCHEMBL24013109 0.79 RCE1 (0.39) RCE1HTTKMT2AMAPTNPC1
SCHEMBL4519983 0.78 SLC1A3 (0.42) RCE1HTTKMT2AMAPTSLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005037803-A1 ORGANIC COMPOUNDS SPEEDEL EXPERIMENTA AG (CH) 2005-04-28 WO disclosed