Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15441675 | 0.85 | CETP (0.39) | KMT2ACETPCSNK1ECNR2ALDH1A1 | |
| SCHEMBL4259382 | 0.83 | CTSL (0.40) | KMT2ACETPCSNK1ECNR2ALDH1A1 | |
| SCHEMBL21677653 | 0.82 | RCE1 (0.49) | RCE1HTTNPC1KMT2AALDH1A1 | |
| SCHEMBL3335354 | 0.81 | CETP (0.36) | CETPCSNK1ECNR2ALDH1A1CYP3A4 | |
| SCHEMBL4259393 | 0.81 | CETP (0.39) | RCE1KMT2ACETPCSNK1ECNR2 | |
| SCHEMBL1056428 | 0.81 | RCE1 (0.46) | RCE1HTTNPC1KMT2AALDH1A1 | |
| SCHEMBL6512943 | 0.81 | RCE1 (0.49) | RCE1HTTNPC1KMT2AALDH1A1 | |
| SCHEMBL30524953 | 0.80 | CETP (0.42) | KMT2ACETPCSNK1ECNR2ALDH1A1 | |
| SCHEMBL2640220 | 0.80 | TSHR (0.44) | RCE1KMT2ACETPALDH1A1TSHR | |
| SCHEMBL28246143 | 0.80 | RCE1 (0.50) | RCE1HTTNPC1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124810-A1 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026202-A1 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-05-11 | — | — | WO | disclosed |