Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510425 | 0.95 | MEN1 (0.52) | ALDH1A1SMN1; SMN2ALOX12MEN1KMT2A | |
| SCHEMBL11865912 | 0.78 | ERCC5 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AERCC5 | |
| SCHEMBL14521488 | 0.77 | MEN1 (0.52) | ALDH1A1SMN1; SMN2ALOX12MEN1KMT2A | |
| SCHEMBL940303 | 0.77 | MEN1 (0.52) | ALDH1A1SMN1; SMN2ALOX12MEN1KMT2A | |
| SCHEMBL11216066 | 0.74 | MEN1 (0.62) | ALDH1A1SMN1; SMN2ALOX12MEN1KMT2A | |
| SCHEMBL3231208 | 0.72 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2ALOX12MEN1KMT2A | |
| SCHEMBL6768977 | 0.72 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2ALOX12MEN1KMT2A | |
| SCHEMBL11696636 | 0.71 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2ALOX12MEN1KMT2A | |
| SCHEMBL6817570 | 0.71 | MEN1 (0.58) | ALDH1A1SMN1; SMN2ALOX12MEN1KMT2A | |
| SCHEMBL8755694 | 0.71 | KMT2A (0.64) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005035526-A1 | BICYCLIC COMPOUNDS AND THEIR THERAPEUTIC USE | ARGENTA DISCOVERY LTD. (GB) | 2005-04-21 | — | — | WO | disclosed |