Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.54 |
| ▸ | FEN1 | P39748 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11761251 | 0.82 | ERCC5 (0.58) | ERCC5FEN1ALDH1A1PARP1P2RX7 | |
| SCHEMBL6510425 | 0.82 | MEN1 (0.52) | ERCC5FEN1ALDH1A1CYP2C19MEN1 | |
| SCHEMBL7438839 | 0.81 | ERCC5 (0.57) | ERCC5FEN1ALDH1A1PARP1P2RX7 | |
| SCHEMBL8858796 | 0.79 | ERCC5 (0.59) | ERCC5FEN1ALDH1A1P2RX7CYP2C19 | |
| SCHEMBL7690326 | 0.79 | ERCC5 (0.64) | ERCC5FEN1ALDH1A1PARP1P2RX7 | |
| SCHEMBL18410881 | 0.78 | ERCC5 (0.62) | ERCC5FEN1ALDH1A1PARP1P2RX7 | |
| SCHEMBL6488926 | 0.78 | ERCC5 (0.62) | ERCC5FEN1ALDH1A1PARP1P2RX7 | |
| SCHEMBL10783237 | 0.78 | ERCC5 (0.54) | ERCC5FEN1ALDH1A1PARP1CYP2C19 | |
| SCHEMBL6513074 | 0.78 | ALDH1A1 (0.47) | ERCC5FEN1ALDH1A1CYP2C19MEN1 | |
| SCHEMBL29962144 | 0.77 | ERCC5 (0.76) | ERCC5FEN1PARP1P2RX7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3950526-A | Quinazoline derivatives in pharmaceutical compositions for treating pain and inflammation | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-13 | — | — | US | disclosed |