Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513262 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CES2CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL6304083 | 0.85 | ALDH1A1 (0.45) | ALDH1A1CES2CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL6304079 | 0.85 | ALDH1A1 (0.45) | ALDH1A1CES2CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL6306818 | 0.85 | ALDH1A1 (0.45) | ALDH1A1CES2CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL9516043 | 0.80 | ALDH1A1 (0.60) | ALDH1A1CES2CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL17838017 | 0.74 | TDP1 (0.50) | ALDH1A1CES2CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL17837383 | 0.74 | TDP1 (0.50) | ALDH1A1CES2CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL13983338 | 0.74 | ALDH1A1 (0.57) | ALDH1A1CES2CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL22915747 | 0.74 | ALDH1A1 (0.55) | ALDH1A1CES2CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL22915744 | 0.74 | ALDH1A1 (0.55) | ALDH1A1CES2CHRNB2CHRNA5CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119286-A1 | BETA-2'-OR 3'-HALONUCLEOSIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119286-A1 | BETA-2'-OR 3'-HALONUCLEOSIDES | MKI67, EBP, PCNA | ALDH1A1 2973/4885CES2 465/4885CHRNB2 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.