Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27277447 | 1.00 | TDP1 (0.58) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL7522418 | 1.00 | TDP1 (0.58) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL9699333 | 1.00 | TDP1 (0.58) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL9699338 | 1.00 | TDP1 (0.58) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL9099342 | 1.00 | TDP1 (0.58) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL1132359 | 0.92 | TDP1 (0.59) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL11015972 | 0.92 | TDP1 (0.59) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL7804219 | 0.92 | TDP1 (0.59) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL10579475 | 0.92 | TDP1 (0.59) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL9642504 | 0.92 | TDP1 (0.59) | TDP1CTDSP1MAPK1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100367-A1 | INTERMEDIATES USEFUL IN THE SYNTHESIS OF 3-(2-SUBSTITUTED VINYL) CEPHALOSPORINS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | disclosed |
| EP-0236231-B1 | Novel cephem compounds | MEIJI SEIKA KAISHA (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5171854-A | Antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-15 | — | — | US | disclosed |
| EP-0145906-B1 | CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-5073551-A | Antibiotics | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-12-17 | — | — | US | disclosed |
| US-4918068-A | ACTIVE AGAINST GRAM POSITIVE BACTERIA | MEIJI SEIKA KAISHA, LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0335390-A2 | Novel cephalosporin compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-10-04 | — | — | EP | disclosed |
| EP-0236231-A2 | Novel cephem compounds | MEIJI SEIKA KAISHA LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |
| US-4632918-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-30 | — | — | US | disclosed |
| US-4622318-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-11-11 | — | — | US | disclosed |
| EP-0145906-A2 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-26 | — | — | EP | disclosed |
| US-4354022-A | Process for preparing 3-methylenecepham compounds or a salt thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-12 | — | — | US | disclosed |