Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6518506 | 0.85 | CFTR (0.49) | ALDH1A1LMNAKDM4EHPGDGFER | |
| SCHEMBL6520247 | 0.83 | ALDH1A1 (0.40) | ALDH1A1LMNAKDM4EHPGDGFER | |
| SCHEMBL29077097 | 0.71 | ALDH1A1 (0.57) | ALDH1A1LMNAKDM4EHPGDNPSR1 | |
| SCHEMBL30581234 | 0.71 | ALDH1A1 (0.57) | ALDH1A1LMNAKDM4EHPGDNPSR1 | |
| SCHEMBL6515682 | 0.67 | ATM (0.53) | ALDH1A1LMNAKDM4ECFTRNPSR1 | |
| SCHEMBL6514222 | 0.67 | ALDH1A1 (0.59) | ALDH1A1LMNAKDM4EHPGDGFER | |
| SCHEMBL30581249 | 0.67 | KDM4E (0.60) | ALDH1A1LMNAKDM4EHPGDNPSR1 | |
| SCHEMBL29076186 | 0.67 | KDM4E (0.60) | ALDH1A1LMNAKDM4EHPGDNPSR1 | |
| SCHEMBL6512290 | 0.66 | ATM (0.40) | ALDH1A1TDP1 | |
| SCHEMBL541489 | 0.66 | TDP1 (0.72) | ALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239767-A1 | Intermolecular SNAr of the heterocycle-activated nitro and fluoro groups-application in the synthesis of polyazamacrocyclic ligands | NATIONAL SCIENCE FOUNDATION | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239767-A1 | Intermolecular SNAr of the heterocycle-activated nitro and fluoro groups-application in the synthesis of polyazamacrocyclic ligands | TECR, PAICS, DCXR | ALDH1A1 1812/4885LMNA 1745/4885KDM4E 1602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.