Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513817 | 0.91 | FFAR4 (0.41) | ENPP2MAPTMAPK1FFAR1FFAR4 | |
| SCHEMBL6508828 | 0.88 | MAPT (0.43) | ENPP2MAPTMAPK1FFAR4CETP | |
| SCHEMBL6516543 | 0.87 | FFAR4 (0.49) | FFAR1KAT6AFFAR4CETP | |
| SCHEMBL6512693 | 0.85 | TSHR (0.49) | FFAR1FFAR4CETPPTGES | |
| SCHEMBL6513365 | 0.84 | ENPP2 (0.39) | ENPP2MAPTMAPK1FFAR1KAT6A | |
| SCHEMBL6515075 | 0.83 | GAA (0.41) | — | |
| SCHEMBL6533389 | 0.82 | MAPT (0.41) | ENPP2MAPTMAPK1FFAR1KAT6A | |
| SCHEMBL6532728 | 0.81 | ATM (0.39) | FFAR4PTGS1PTGS2MEP1B | |
| SCHEMBL6531269 | 0.79 | FFAR4 (0.38) | ENPP2MAPTMAPK1FFAR1FFAR4 | |
| SCHEMBL6513425 | 0.79 | FFAR4 (0.42) | ENPP2MAPTMAPK1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |