Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ACSL1 | P33121 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513817 | 0.88 | FFAR4 (0.41) | MAPTMAPK1KCNH2MEP1BCETP | |
| SCHEMBL6513753 | 0.88 | ENPP2 (0.40) | MAPTMAPK1MEP1BCETPSLC6A9 | |
| SCHEMBL6533389 | 0.87 | MAPT (0.41) | MAPTMAPK1MEP1BCETPSLC6A9 | |
| SCHEMBL6513425 | 0.86 | FFAR4 (0.42) | MAPTMAPK1OPRM1OPRD1OPRK1 | |
| SCHEMBL6509243 | 0.84 | SLC2A1 (0.48) | NPC1MEN1KMT2ACETPFFAR4 | |
| SCHEMBL6513365 | 0.84 | ENPP2 (0.39) | MAPTMAPK1MEP1BCETPSLC6A9 | |
| SCHEMBL6531269 | 0.82 | FFAR4 (0.38) | MAPTMAPK1MEP1BCETPSLC6A9 | |
| SCHEMBL6518913 | 0.81 | NPC1 (0.50) | NPC1 | |
| SCHEMBL6515065 | 0.81 | TSHR (0.55) | FFAR4 | |
| SCHEMBL6515378 | 0.80 | FFAR1 (0.52) | MEP1BFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |