SCHEMBL6513808

SCHEMBL6513808

Cc1ccc2ccccc2c1C1=CC(=O)C=CC1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 2/20 0.54
CCR6 P51684 1/20 0.54
CES1 P23141 2/20 0.46
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
CYP1A2 P05177 2/20 0.43
TSHR P16473 2/20 0.43
CYP2A6 P11509 2/20 0.43
NSD2 O96028 1/20 0.42
OPRM1 P35372 1/20 0.42
OPRD1 P41143 1/20 0.42
HSD17B3 P37058 1/20 0.42
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 2/20 0.41
MAPK1 P28482 2/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11577947 0.92 CYP1A2 (0.53) HKDC1CCR6CES1MAOAMAOB
SCHEMBL23175329 0.86 HKDC1 (0.47) HKDC1CCR6CES1MAOAMAOB
SCHEMBL27572489 0.81 HKDC1 (0.48) HKDC1CCR6CES1MAOAMAOB
SCHEMBL15551466 0.81 HKDC1 (0.47) HKDC1CCR6CES1MAOAMAOB
SCHEMBL28031782 0.81 HKDC1 (0.50) HKDC1CCR6CES1MAOAMAOB
SCHEMBL9387839 0.81 HKDC1 (0.60) HKDC1CCR6CES1MAOAMAOB
SCHEMBL9388858 0.80 MAPT (0.60) HKDC1CCR6CES1MAOAMAOB
SCHEMBL27732024 0.80 HKDC1 (0.51) HKDC1CCR6CES1MAOAMAOB
SCHEMBL7914952 0.77 ALDH1A1 (0.53) HKDC1CCR6CES1MAOAMAOB
SCHEMBL10704950 0.77 CCR6 (0.51) HKDC1CCR6MAOAMAOBHSD17B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050089890-A1 Multimolecular devices and drug delivery systems CUBICCIOTTI ROGER S (US) 2005-04-28 US disclosed
US-6762025-B2 SYNTHETIC NUCLEOTIDE SEQUENCES; GENERATE SEQUENCES, INCUBATE WITH PREFERENTIAL NUCLEOTIDE SEQUENCES, MONITOR SAMPLES FOR BINDING MOLECULAR MACHINES, INC. 2004-07-13 US disclosed
US-20020034757-A1 Single-molecule selection methods and compositions therefrom CUBICCIOTTI ROGER S (US) 2002-03-21 US disclosed
US-6287765-B1 SYNTHETIC HETEROPOLYMERS, OLIGONUCLEOTIDE MOLECULE CAPABLE OF SPECIFICALLY BINDING TO NONOLIGONUCLEOTIDE; TEMPLATE-DIRECTED MOLECULAR ASSEMBLY AND DEVICE INTEGRATION; DRUG DELIVERY SYSTEMS, SENSORS, SWITCHES, TRANSDUCERS MOLECULAR MACHINES, INC. 2001-09-11 US disclosed
US-5773635-A ALDOL CONDENSATION; IN PRESENCE OF OXYGEN OR NITRIC OXIDE BASF AKTIENGESELLSCHAFT (DE) 1998-06-30 US disclosed
US-4482492-A Preparation of vitamins K3 and K4 and derivatives BASF AKTIENGESELLSCHAFT (DE) 1984-11-13 US disclosed