Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766994 | 0.84 | ALDH1A1 (0.49) | ALDH1A1SLC1A5TDP1KMT2AMAPK1 | |
| SCHEMBL21385349 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SLC1A5TDP1KMT2AMAPK1 | |
| SCHEMBL21081465 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SLC1A5TDP1KMT2AMAPK1 | |
| SCHEMBL28276065 | 0.82 | KMT2A (0.50) | ALDH1A1TDP1KMT2AMAPK1LMNA | |
| SCHEMBL6523606 | 0.81 | ALDH1A1 (0.46) | ALDH1A1SLC1A5TDP1KMT2AMAPK1 | |
| SCHEMBL21081464 | 0.81 | MAPK1 (0.47) | ALDH1A1SLC1A5TDP1KMT2AMAPK1 | |
| SCHEMBL2638485 | 0.81 | SLC7A5 (0.58) | ALDH1A1SLC1A5TDP1KMT2ASLC6A2 | |
| SCHEMBL28311549 | 0.81 | KMT2A (0.49) | ALDH1A1TDP1KMT2AMAPK1LMNA | |
| SCHEMBL24247679 | 0.80 | LARS1 (0.46) | ALDH1A1SLC1A5TDP1KMT2AMAPK1 | |
| SCHEMBL28361736 | 0.80 | SLC7A5 (0.56) | ALDH1A1SLC1A5TDP1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272677-A1 | Delivery of a substance to a pre-determined site | APPLIED NANOSYSTEMS B.V. (NL) | 2005-12-08 | — | — | US | disclosed |
| EP-1490028-A1 | DELIVERY OF A SUBSTANCE TO A PRE-DETERMINED SITE | Applied NanoSystems B.V. (NL) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003084508-A1 | DELIVERY OF A SUBSTANCE TO A PRE-DETERMINED SITE | APPLIED NANOSYSTEMS B.V. (NL) | 2003-10-16 | — | — | WO | disclosed |
| WO-2000063394-A9 | A POLYPEPTIDE HAVING AMIDOLYTIC ACTIVITY FOR A SERPIN | UNIV GEORGIA RES FOUND (US) | 2002-06-27 | — | — | WO | disclosed |
| WO-2000063394-A2 | A POLYPEPTIDE HAVING AMIDOLYTIC ACTIVITY FOR A SERPIN | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2000-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272677-A1 | Delivery of a substance to a pre-determined site | TACR1, TACR2, NPSR1 | ALDH1A1 788/4885SLC1A5 775/4885TDP1 3574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.