Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21385349 | 0.98 | ALDH1A1 (0.47) | ALDH1A1SLC1A5TDP1PRKCAKMT2A | |
| SCHEMBL20456558 | 0.90 | SLC1A5 (0.61) | ALDH1A1SLC1A5PRKCAHIF1ALMNA | |
| SCHEMBL6523606 | 0.86 | ALDH1A1 (0.46) | ALDH1A1SLC1A5TDP1PRKCAKMT2A | |
| SCHEMBL6514022 | 0.84 | ALDH1A1 (0.47) | ALDH1A1SLC1A5TDP1PRKCAKMT2A | |
| SCHEMBL21081465 | 0.84 | ALDH1A1 (0.47) | ALDH1A1SLC1A5TDP1PRKCAKMT2A | |
| SCHEMBL21081464 | 0.83 | MAPK1 (0.47) | ALDH1A1SLC1A5TDP1PRKCAKMT2A | |
| SCHEMBL2638485 | 0.83 | SLC7A5 (0.58) | ALDH1A1SLC1A5TDP1KMT2ASLC6A2 | |
| SCHEMBL24247679 | 0.81 | LARS1 (0.46) | ALDH1A1SLC1A5TDP1KMT2AMAPK1 | |
| SCHEMBL28361736 | 0.81 | SLC7A5 (0.56) | ALDH1A1SLC1A5TDP1KMT2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL6751555 | 0.81 | SLC1A5 (0.51) | ALDH1A1SLC1A5TDP1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106748966-B | A kind of synthetic method of Ramipril key intermediate | 浙江工业大学 | 2019-09-03 | — | — | CN | claimed |
| CN-106748966-A | A kind of synthetic method of Ramipril key intermediate | 浙江工业大学 | 2017-05-31 | — | — | CN | claimed |
| EP-1105416-A1 | NOVEL PROCESS FOR THE SYNTHESIS OF EXOCHELINS | Keystone Biomedical, Inc. (US) | 2001-06-13 | — | — | EP | claimed |
| WO-2000009547-A1 | NOVEL PROCESS FOR THE SYNTHESIS OF EXOCHELINS | KEYSTONE BIOMEDICAL, INC. (US) | 2000-02-24 | — | — | WO | claimed |
| CN-106748966-B | A kind of synthetic method of Ramipril key intermediate | 浙江工业大学 | 2019-09-03 | — | — | CN | disclosed |
| CN-106748966-A | A kind of synthetic method of Ramipril key intermediate | 浙江工业大学 | 2017-05-31 | — | — | CN | disclosed |
| CN-102711720-A | Pigmentation preventing or improving agent | POLA CHEM IND INC | 2012-10-03 | — | — | CN | disclosed |
| US-6063919-A | ESTERIFICATION OF O-DEPROTECTED DIBENZYL EXOCHELIC ACID WITH BENZYL EPI-COBACTIN, HYDROGENOLYTICALLY REMOVING THE THREE BENZYL GROUPS TO FORM EXOCHELIN 786SM(R) | KEYSTONE BIOMEDICAL, INC. (US) | 2000-05-16 | — | — | US | disclosed |
| EP-0785768-A4 | — | — | 1997-07-30 | — | — | EP | disclosed |
| EP-0785768-A1 | O-ACYL SERINES AS DEODORANTS | THE GILLETTE COMPANY (US) | 1997-07-30 | — | — | EP | disclosed |
| WO-1995007069-A1 | O-ACYL SERINES AS DEODORANTS | THE GILLETTE COMPANY (US) | 1995-03-16 | — | — | WO | disclosed |
| EP-0368253-A2 | Delivery system for pharmaceutical or therapeutic actives | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (a New York corporation) (US) | 1990-05-16 | — | — | EP | disclosed |