Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2888538 | 0.82 | OPRM1 (0.48) | OPRD1OPRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL6514283 | 0.81 | OPRD1 (0.44) | OPRD1OPRM1CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL3847452 | 0.81 | OPRM1 (0.47) | OPRD1OPRM1CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL5198335 | 0.73 | OPRM1 (0.41) | OPRD1OPRM1CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL3942210 | 0.73 | MEN1 (0.49) | OPRD1OPRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL85392 | 0.71 | OPRM1 (0.48) | OPRD1OPRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL23206062 | 0.70 | OPRD1 (0.43) | OPRD1OPRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL14491539 | 0.68 | DPP4 (0.50) | OPRD1OPRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL6843039 | 0.68 | OPRM1 (0.53) | OPRD1OPRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL5074955 | 0.68 | OPRD1 (0.52) | OPRD1OPRM1SLC6A9OPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019168-A2 | FLUORINATED LYSINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS | PFIZER PRODUCTS INC. (US) | 2005-03-03 | — | — | WO | disclosed |