SCHEMBL6514469

SCHEMBL6514469

CCOCCCCCCC(CC(=O)Oc1ccccc1)=C(CC(=O)O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.46
HDAC1 Q13547 3/20 0.41
HDAC2 Q92769 3/20 0.41
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
FAAH O00519 6/20 0.38
ALDH1A1 P00352 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
EPHX2 P34913 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6520975 0.88 ZDHHC2 (0.44) SMN1; SMN2PRSS1PRSS2PRSS3FAAH
SCHEMBL6515099 0.85 TSHR (0.44) SMN1; SMN2FAAHALDH1A1L3MBTL1
SCHEMBL6518836 0.84 EPHX2 (0.41) SMN1; SMN2ALDH1A1KMT2AKDM4EMEN1
SCHEMBL19543185 0.81 PRSS1 (0.55) SMN1; SMN2HDAC1HDAC2PRSS1PRSS2
SCHEMBL1066224 0.81 FNTA (0.46) SMN1; SMN2ALDH1A1KMT2AMEN1EPHX2
SCHEMBL6518690 0.80 KMT2A (0.42) HDAC1HDAC2PRSS1PRSS2PRSS3
SCHEMBL19543188 0.79 PRSS1 (0.52) SMN1; SMN2HDAC1HDAC2PRSS1PRSS2
SCHEMBL6522453 0.79 CYP19A1 (0.42) PRSS1PRSS2PRSS3ALDH1A1KMT2A
SCHEMBL6514767 0.79 KMT2A (0.42) SMN1; SMN2ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL6513569 0.79 FNTA (0.46) SMN1; SMN2ALDH1A1KDM4EEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958366-B2 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-25 US disclosed
US-20030118544-A1 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118544-A1 Antifouling coating composition and novel resin COL1A1, GLRA1, COL2A1 SMN1; SMN2 1768/4885HDAC1 1256/4885HDAC2 2474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.