SCHEMBL6514692

SCHEMBL6514692

OCC(CO)NC(CO)CO

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
CNR1 P21554 1/20 0.40
ADRA1A P35348 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ABCC3 O15438 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13101426 0.83 LMNA (0.57) LMNATDP1CNR1ADRA1AKDM4E
SCHEMBL3353769 0.78 LMNA (0.60) LMNATDP1CNR1ADRA1AKDM4E
SCHEMBL2606746 0.78
SCHEMBL7592324 0.75
SCHEMBL11745129 0.70
SCHEMBL20988101 0.67 LMNA (0.48) LMNATDP1CNR1ADRA1AKDM4E
SCHEMBL23606873 0.67
SCHEMBL7951950 0.67
SCHEMBL15630450 0.67
SCHEMBL5775460 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8653306-B1 Process for production of serinol and its bis-adduct Penn A Kem LLC (US) 2014-02-18 US claimed
EP-1159255-A2 BIS(1,3-DIHYDROXY-PROP-2-YL)AMINE AND DERIVATIVES THEREOF IN THE MANUFACTURE OF POLYMERS ISIS INNOVATION LIMITED (GB) 2001-12-05 EP claimed
WO-2000055111-A2 BIS(1,3-DIHYDROXY-PROP-2-YL)AMINE AND DERIVATIVES THEREOF IN THE MANUFACTURE OF POLYMERS ISIS INNOVATION LIMITED (GB) 2000-09-21 WO claimed
US-20260125344-A1 POLYURETHANE-ACETOACETATE COMPOUNDS PPG INDUSTRIES OHIO, INC. (US) 2026-05-07 US disclosed
EP-4423059-A2 POLYURETHANE-ACETOACETATE COMPOUNDS PPG Industries Ohio, Inc. (US) 2024-09-04 EP disclosed
WO-2023076835-A2 POLYURETHANE-ACETOACETATE COMPOUNDS PPG INDUSTRIES OHIO, INC. (US) 2023-05-04 WO disclosed
US-8653306-B1 Process for production of serinol and its bis-adduct Penn A Kem LLC (US) 2014-02-18 US disclosed
US-8653306-B1 Process for production of serinol and its bis-adduct Penn A Kem LLC (US) 2014-02-18 US disclosed
US-6916948-B2 Bis(1,3-dihydroxy-prop-2-yl) amine and derivatives thereof in the manufacture of polymers ISIS INNOVATION LIMITED (GB) 2005-07-12 US disclosed
US-6916948-B2 Bis(1,3-dihydroxy-prop-2-yl) amine and derivatives thereof in the manufacture of polymers ISIS INNOVATION LIMITED (GB) 2005-07-12 US disclosed
US-6916948-B2 Bis(1,3-dihydroxy-prop-2-yl) amine and derivatives thereof in the manufacture of polymers ISIS INNOVATION LIMITED (GB) 2005-07-12 US disclosed
EP-0839032-A4 HYDROXYL IONS AS UNIQUE THERAPEUTIC AGENTS AND COMPOUNDS THAT MODULATE IONS, COMPOUNDS FHJ SCIENT INC (US) 1998-07-08 EP disclosed
EP-0839032-A1 HYDROXYL IONS AS UNIQUE THERAPEUTIC AGENTS AND COMPOUNDS THAT MODULATE IONS, COMPOUNDS FHJ SCIENTIFIC, INC. (US) 1998-05-06 EP disclosed
US-5679711-A Hydroxyl ions as novel therapeutic agents and compounds that modulate these ions, compositions employing these agents, therapeutic methods for using such agents FHJ SCIENTIFIC, INC. (US) 1997-10-21 US disclosed
WO-1996040104-A1 HYDROXYL IONS AS UNIQUE THERAPEUTIC AGENTS AND COMPOUNDS THAT MODULATE IONS, COMPOUNDS FHJ SCIENTIFIC, INC. (US) 1996-12-19 WO disclosed
US-5585391-A Hydroxyl ions as unique therapeutic agents and compounds that modulate these ions, compositions employing these agents, therapeutic methods for using such agents and processes for preparing them FHJ SCIENTIFIC, INC. (US) 1996-12-17 US disclosed
US-5574050-A Hydroxyl ions as unique therapeutic agents and processes for preparing them FHJ SCIENTIFIC, INC. (US) 1996-11-12 US disclosed
EP-0725636-A1 HYDROXYL IONS AS UNIQUE THERAPEUTIC AGENTS AND COMPOUNDS THAT MODULATE THESE IONS, COMPOSITIONS EMPLOYING THESE AGENTS, THERAPEUTIC METHODS FOR USING SUCH AGENTS AND PROCESSES FOR PREPARING THEM FHJ SCIENTIFIC, INC. (US) 1996-08-14 EP disclosed
US-5514808-A Hydroxyl ions as unique therapeutic agents and compounds that modulate these ions FHJ SCIENTIFIC, INC (US) 1996-05-07 US disclosed
WO-1995010272-A1 HYDROXYL IONS AS UNIQUE THERAPEUTIC AGENTS AND COMPOUNDS THAT MODULATE THESE IONS, COMPOSITIONS EMPLOYING THESE AGENTS, THERAPEUTIC METHODS FOR USING SUCH AGENTS AND PROCESSES FOR PREPARING THEM FHJ SCIENTIFIC, INC. (US) 1995-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125344-A1 POLYURETHANE-ACETOACETATE COMPOUNDS HAT1, PUF60, GAR1 LMNA 1125/4885TDP1 953/4885CNR1 2721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.