⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23129904 | 0.76 | — | — | |
| SCHEMBL4159987 | 0.72 | LDHA (0.35) | — | |
| SCHEMBL2348889 | 0.72 | — | — | |
| SCHEMBL7592323 | 0.72 | — | — | |
| SCHEMBL7583115 | 0.72 | THRB (0.33) | — | |
| SCHEMBL19036479 | 0.72 | — | — | |
| SCHEMBL20180881 | 0.72 | — | — | |
| SCHEMBL12004292 | 0.72 | LMNA (0.52) | — | |
| SCHEMBL2058218 | 0.72 | — | — | |
| SCHEMBL6232385 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201130-B1 | FOR THE THERAPY AND PROPHYLAXIS OF DISORDERS INVOLVING MATRIX-DEGRADING METALLOPROTEINASES; ANTIINFLAMMATORY AGENTS | AVENTIS PHARMA DUETSCHLAND GMBH (DE) | 2001-03-13 | — | — | US | claimed |
| US-4049467-A | DIHYDROXY MALEIC OR TARTARIC ACID OR SALT WITH A FILLER; CLEANING COMPOUND | LEVER BROTHERS COMPANY (US) | 1977-09-20 | — | — | US | claimed |
| CN-116590284-A | Gastric juice sample pretreatment reagent and treatment method for helicobacter pylori nucleic acid extraction | 苏州长柏生物科技有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-111247188-A | Polyurethane foam system | 陶氏环球技术有限责任公司 | 2020-06-05 | — | — | CN | disclosed |
| WO-2018017813-A1 | HIGH POTENCY HOMEOPATHIC GEL FORMULATION | POLICH NANCY JOSEPHINE (US) | 2018-01-25 | — | — | WO | disclosed |
| US-20160324910-A1 | HOMEOPATHIC THERAPEUTIC METHOD AND COMPOSITIONS | CEARNA, INC. | 2016-11-10 | — | — | US | disclosed |
| US-4683330-A | ANTICOAGULANTS, ANTIULCER AGENTS | THE UPJOHN COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| US-4668814-A | ANTIULCER AGENTS, ANTIASHMATICS, ANTICOAGULANTS | THE UPJOHN COMPANY (US) | 1987-05-26 | — | — | US | disclosed |
| US-4628110-A | Novel 9-substituted carbacyclin analogs | THE UPJOHN COMPANY (US) | 1986-12-09 | — | — | US | disclosed |
| US-4621100-A | Treatment of osteoporosis with prostaglandins | THE UPJOHN COMPANY (US) | 1986-11-04 | — | — | US | disclosed |
| EP-0089769-B1 | 9-SUBSTITUTED CARBACYCLIN ANALOGUES | THE UPJOHN COMPANY (US) | 1986-10-01 | — | — | EP | disclosed |
| US-4131738-A | 6-Hydroxy-PGE1 compounds | THE UPJOHN COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4129423-A | Stable liquid abrasive composition suitable for removing manganese-ion derived discolorations from hard surfaces | LEVER BROTHERS COMPANY (US) | 1978-12-12 | — | — | US | disclosed |
| US-4128713-A | 6,7-Didehydro-PGI1 compounds | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
| US-4126744-A | PROSTACYCLIN, MUSCLE STIMULANTS, PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4112224-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4109082-A | PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS | THE UPJOHN COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4100192-A | Inter-phenylene-PG amides | THE UPJOHN COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4097489-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-4049467-A | DIHYDROXY MALEIC OR TARTARIC ACID OR SALT WITH A FILLER; CLEANING COMPOUND | LEVER BROTHERS COMPANY (US) | 1977-09-20 | — | — | US | disclosed |