Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.41 |
| ▸ | FAP | Q12884 | 3/20 | 0.41 |
| ▸ | PEPD | P12955 | 1/20 | 0.39 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | PITRM1 | Q5JRX3 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532912 | 0.82 | DPP4 (0.48) | DPP4DPP8DPP7POLB | |
| SCHEMBL6514705 | 0.80 | DPP4 (0.60) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL6532652 | 0.77 | DPP4 (0.72) | DPP4DPP8DPP7EPHX2 | |
| SCHEMBL6510532 | 0.72 | DPP4 (0.60) | DPP4DPP8DPP7FAPEPHX2 | |
| SCHEMBL3726198 | 0.68 | DPP4 (0.61) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL12463580 | 0.68 | DPP4 (0.61) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL8126121 | 0.68 | DPP4 (0.61) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL9966602 | 0.68 | DPP4 (0.61) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL8243342 | 0.68 | DPP4 (0.61) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL26119597 | 0.68 | DPP4 (0.61) | DPP4DPP8DPP7DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |