SCHEMBL6514738

SCHEMBL6514738

C#CC[C@@]1(n2cc(N)c(=O)[nH]c2=O)O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 7/20 0.44
P2RY6 Q15077 7/20 0.44
P2RY4 P51582 5/20 0.42
POLA1 P09884 2/20 0.39
POLB P06746 1/20 0.39
POLD1 P28340 1/20 0.39
P2RX3 P56373 1/20 0.38
P2RY14 Q15391 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18241039 0.86 P2RY2 (0.44) P2RY2P2RY6P2RY4POLA1POLB
SCHEMBL6511718 0.84 P2RY2 (0.41) P2RY2P2RY6P2RY4P2RX3
SCHEMBL3485976 0.84 P2RY6 (0.41) P2RY2P2RY6P2RY4POLA1POLB
SCHEMBL4010795 0.73 P2RY6 (0.41) P2RY2P2RY6P2RY4POLA1POLB
SCHEMBL5409945 0.73 POLB (0.51) P2RY2P2RY6P2RY4POLA1POLB
SCHEMBL31381447 0.73 P2RY14 (0.56) P2RY2P2RY6P2RY4POLA1P2RY14
SCHEMBL6519317 0.72 P2RY6 (0.73) P2RY2P2RY6P2RY4
SCHEMBL6519315 0.72 P2RY6 (0.73) P2RY2P2RY6P2RY4
SCHEMBL8437841 0.72 P2RY2 (0.59) P2RY2P2RY6P2RY4POLA1
SCHEMBL31309815 0.71 P2RY2 (0.42) P2RY2P2RY6P2RY4P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050214759-A1 Enzymatic redox labelling of nucleic acids WLASSOF WJATSCHESSLAW 2005-09-29 US claimed
EP-1468006-A1 ENZYMATIC REDOX LABELLING OF NUCLEIC ACIDS UNISEARCH LIMITED (AU) 2004-10-20 EP claimed
WO-2003055898-A1 ENZYMATIC REDOX LABELLING OF NUCLEIC ACIDS UNISEARCH LIMITED (AU) 2003-07-10 WO claimed
US-20050214759-A1 Enzymatic redox labelling of nucleic acids WLASSOF WJATSCHESSLAW 2005-09-29 US disclosed
EP-1468006-A1 ENZYMATIC REDOX LABELLING OF NUCLEIC ACIDS UNISEARCH LIMITED (AU) 2004-10-20 EP disclosed
WO-2003055898-A1 ENZYMATIC REDOX LABELLING OF NUCLEIC ACIDS UNISEARCH LIMITED (AU) 2003-07-10 WO disclosed