Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.79 |
| ▸ | PRKCA | P17252 | 2/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.62 |
| ▸ | FAAH | O00519 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | TERT | O14746 | 3/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 3/20 | 0.58 |
| ▸ | PPARD | Q03181 | 3/20 | 0.58 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80898 | 1.00 | LMNA (0.79) | LMNAPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL10338455 | 1.00 | LMNA (0.79) | LMNAPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL18133442 | 1.00 | LMNA (0.79) | LMNAPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL10338452 | 1.00 | LMNA (0.79) | LMNAPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL61998 | 1.00 | LMNA (0.79) | LMNAPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL3656513 | 1.00 | LMNA (0.79) | LMNAPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL6514791 | 1.00 | LMNA (0.79) | LMNAPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL6429415 | 1.00 | LMNA (0.79) | LMNAPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL4124375 | 1.00 | LMNA (0.79) | LMNAPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL28578863 | 1.00 | LMNA (0.79) | LMNAPRKCAPRKCEPRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261222-A1 | Oligoribonucleotides for the treatment of irritative or inflammatory skin symptoms through RNA interference | BEIERSDORF AG | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261222-A1 | Oligoribonucleotides for the treatment of irritative or inflammatory skin symptoms through RNA interference | TLR3, POLR1C, TLR5 | LMNA 3646/4885PRKCA 973/4885PRKCE 2941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.