Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL27338841 | 0.89 | LMNA (0.40) | — | |
| Phosphoric Acid SCHEMBL27569725 | 0.89 | LMNA (0.40) | — | |
| Phosphoric Acid SCHEMBL1230348 | 0.88 | — | — | |
| Phosphoric Acid SCHEMBL27646938 | 0.78 | LMNA (0.40) | — | |
| Phosphoric Acid SCHEMBL22800688 | 0.78 | SLC34A1 (0.39) | — | |
| Phosphoric Acid SCHEMBL25395731 | 0.76 | — | — | |
| Phosphoric Acid SCHEMBL22372390 | 0.76 | SLC34A1 (0.46) | — | |
| Phosphoric Acid SCHEMBL20838149 | 0.76 | — | — | |
| Phosphoric Acid SCHEMBL21951676 | 0.76 | — | — | |
| Phosphoric Acid SCHEMBL22372392 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050196851-A1 | Crystal structure of the BTK kinase domain | PARKER HUGHES INSTITUTE (US) | 2005-09-08 | — | — | US | disclosed |
| WO-2003016338-A9 | CRYSTAL STRUCTURE OF THE BTK KINASE DOMAIN | PARKER HUGHES INST (US) | 2003-07-31 | — | — | WO | disclosed |
| WO-2003016338-A1 | CRYSTAL STRUCTURE OF THE BTK KINASE DOMAIN | PARKER HUGHES INSTITUTE (US) | 2003-02-27 | — | — | WO | disclosed |