Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507704 | 0.87 | CHEK1 (0.49) | CHEK1MEN1KMT2ANPSR1KDM4E | |
| SCHEMBL6509621 | 0.87 | SMN1; SMN2 (0.65) | CHEK1MEN1KMT2AFLT3KDM4E | |
| SCHEMBL6512362 | 0.83 | IKBKB (0.57) | MEN1KMT2ATSHRTDP1L3MBTL1 | |
| SCHEMBL6506340 | 0.82 | FLT3 (0.51) | MEN1KMT2ANPSR1FLT3KDM4E | |
| SCHEMBL6510833 | 0.81 | IKBKB (0.53) | CHEK1MEN1KMT2ATDP1IKBKB | |
| SCHEMBL6530168 | 0.81 | IKBKB (0.62) | CHEK1MEN1KMT2ANPSR1TDP1 | |
| SCHEMBL6511724 | 0.81 | MAPT (0.51) | CHEK1MEN1KMT2ANPSR1FLT3 | |
| SCHEMBL7006938 | 0.81 | KDR (0.65) | CHEK1MEN1KMT2ANPSR1KDM4E | |
| SCHEMBL6510003 | 0.80 | P2RX1 (0.52) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL6507728 | 0.80 | IKBKB (0.50) | MEN1KMT2AKDM4ETDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105777-A1 | SUBSTITUTED THIOPHENE AMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-11-10 | — | — | WO | disclosed |