SCHEMBL6515052

SCHEMBL6515052

Cc1ccc(F)c(CN(CCC(=O)O)Cc2cccc(CCC(C)C)c2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.40
CSF3R Q99062 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
SLC1A5 Q15758 1/20 0.39
GAA P10253 1/20 0.39
PTGER1 P34995 1/20 0.37
PTGER4 P35408 1/20 0.37
PTGER3 P43115 1/20 0.37
PTGER2 P43116 1/20 0.37
OPRM1 P35372 4/20 0.37
OPRD1 P41143 4/20 0.37
OPRK1 P41145 4/20 0.37
POLB P06746 1/20 0.36
FFAR1 O14842 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
LMNA P02545 1/20 0.36
PKM P14618 1/20 0.36
HTT P42858 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6515089 0.92 POLB (0.42) CSF3RMEN1KMT2ASLC1A5PTGER1
SCHEMBL6510695 0.90 FFAR1 (0.43) CSF3RMEN1KMT2ASLC1A5PTGER1
SCHEMBL6532421 0.88 SLC1A5 (0.43) RAB9ACSF3RMEN1KMT2ASLC1A5
SCHEMBL6510860 0.86 RAB9A (0.41) RAB9APTGER1PTGER4PTGER3PTGER2
SCHEMBL6510672 0.85 RAB9A (0.42) RAB9APTGER1PTGER4PTGER3PTGER2
SCHEMBL6511151 0.85 RAB9A (0.43) RAB9ASLC1A5PTGER1PTGER4PTGER3
SCHEMBL6531857 0.84 PPARA (0.42) RAB9A
SCHEMBL6508931 0.84 CSF3R (0.39) CSF3RMEN1KMT2AGAAOPRM1
SCHEMBL6512693 0.81 TSHR (0.49) RAB9APTGER3FFAR1FFAR4
SCHEMBL6532738 0.81 MEN1 (0.52) MEN1KMT2ASLC1A5FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005097100-A2 ANTIBACTERIAL AGENTS PROLYSIS LTD. (GB) 2005-10-20 WO disclosed