Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533664 | 0.90 | MEN1 (0.51) | MEN1KMT2AFFAR4FFAR1SLC1A5 | |
| SCHEMBL6516529 | 0.89 | MEN1 (0.59) | MEN1KMT2AFFAR4FFAR1CETP | |
| SCHEMBL6511151 | 0.84 | RAB9A (0.43) | FFAR4FFAR1SLC1A5LMNA | |
| SCHEMBL6512693 | 0.83 | TSHR (0.49) | FFAR4FFAR1CETPPTGESNR3C1 | |
| SCHEMBL6510860 | 0.82 | RAB9A (0.41) | FFAR4FFAR1 | |
| SCHEMBL6509442 | 0.82 | RAB9A (0.41) | FFAR4FFAR1SLC1A5LMNA | |
| SCHEMBL6510672 | 0.81 | RAB9A (0.42) | — | |
| SCHEMBL6515052 | 0.81 | RAB9A (0.40) | MEN1KMT2AFFAR4FFAR1SLC1A5 | |
| SCHEMBL6531857 | 0.80 | PPARA (0.42) | THRATHRB | |
| SCHEMBL6515075 | 0.79 | GAA (0.41) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |