Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425913 | 1.00 | PPARG (0.50) | PPARGPPARABLMSRRMMP7 | |
| SCHEMBL6903818 | 0.88 | PPARG (0.52) | PPARGPPARABLMSRR | |
| SCHEMBL8142297 | 0.86 | MEN1 (0.43) | PPARGPPARABLM | |
| SCHEMBL7344531 | 0.86 | BLM (0.41) | PPARGPPARABLM | |
| SCHEMBL5012826 | 0.86 | BLM (0.41) | PPARGPPARABLM | |
| SCHEMBL7728941 | 0.86 | MEN1 (0.43) | PPARGPPARABLM | |
| SCHEMBL7375987 | 0.86 | BLM (0.41) | PPARGPPARABLM | |
| SCHEMBL7726567 | 0.86 | MEN1 (0.43) | PPARGPPARABLM | |
| SCHEMBL1858577 | 0.85 | SMN1; SMN2 (0.46) | PPARGPPARABLM | |
| SCHEMBL9773201 | 0.85 | SMN1; SMN2 (0.46) | PPARGPPARABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585744-A | Process for the preparation of benazepril | RANBAXY LAB LTD (IN) | 2005-02-23 | — | — | CN | disclosed |
| WO-2005003134-A1 | A NOVEL PROCESS FOR THE PREPARATION OF CILAZAPRIL | HETERO DRUGS LIMITED (IN) | 2005-01-13 | — | — | WO | disclosed |
| EP-0836610-A1 | DIGLYCOSYLATED 1,2-DIOLS AS MIMETICS OF SIALYL-LEWIS X AND SIALYL-LEWIS A | Novartis AG (CH) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997001569-A1 | DIGLYCOSYLATED 1,2-DIOLS AS MIMETICS OF SIALYL-LEWIS X AND SIALYL-LEWIS A | NOVARTIS AG (CH) | 1997-01-16 | — | — | WO | disclosed |
| EP-0094095-B1 | BICYCLIC CARBOXYLIC ACIDS AND THEIR ALKYL AND ARALKYL ESTERS | F. HOFFMANN-LA ROCHE AG (CH) | 1990-09-19 | — | — | EP | disclosed |
| EP-0094095-A2 | Bicyclic carboxylic acids and their alkyl and aralkyl esters | F. HOFFMANN-LA ROCHE AG (CH) | 1983-11-16 | — | — | EP | disclosed |