SCHEMBL6903818

SCHEMBL6903818

O=C(O)C(CCc1ccccc1)OS(=O)(=O)F

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARG P37231 9/20 0.52
PPARA Q07869 8/20 0.52
BLM P54132 1/20 0.47
SRR Q9GZT4 2/20 0.44
ACE P12821 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6515182 0.88 PPARG (0.50) PPARGPPARABLMSRR
SCHEMBL7425913 0.88 PPARG (0.50) PPARGPPARABLMSRR
SCHEMBL6171190 0.84 PPARG (0.52) PPARGPPARABLMSRRACE
SCHEMBL18063399 0.84 BLM (0.61) PPARGPPARABLMSRR
SCHEMBL6171187 0.84 PPARG (0.52) PPARGPPARABLMSRRACE
SCHEMBL7722450 0.84 SMN1; SMN2 (0.48) PPARGPPARAACE
SCHEMBL9776543 0.81 PPARG (0.47) PPARGPPARABLMSRR
SCHEMBL6907074 0.80 PPARG (0.49) PPARGPPARABLMACE
SCHEMBL6903829 0.80 PPARG (0.49) PPARGPPARABLMSRRACE
SCHEMBL7495011 0.79 PPARG (0.61) PPARGPPARASRRACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1075463-B1 CONVERSION OF A HYDROXY GROUP IN CERTAIN ALCOHOLS INTO A FLUOROSULFONATE ESTER OR A TRIFLUOROMETHYLSULFONATE ESTER LOEWENTHAL HANS JACOB EDGAR (IL) 2004-06-16 EP disclosed
US-6395918-B1 Conversion of a hydroxy group in certain alcohols into a fluorosulfonate ester or a trifluoromethylsulfonate ester LOEWENTHAL HANS JACOB EDGAR (IL) 2002-05-28 US disclosed