Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.39 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401504 | 0.80 | — | — | |
| SCHEMBL9131916 | 0.76 | ACHE (0.35) | ALOX5PTGS2 | |
| SCHEMBL11112146 | 0.75 | BRD4 (0.46) | CYP1A2CYP4F2CYP4A11BRD4ALDH1A1 | |
| SCHEMBL7739836 | 0.74 | ACHE (0.42) | ALOX5PTGS2 | |
| SCHEMBL9277152 | 0.74 | — | — | |
| SCHEMBL20569200 | 0.73 | CYP4F2 (0.47) | CYP1A2CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL15054116 | 0.73 | POLB (0.36) | CYP1A2ALDH1A1CYP3A4GAACYP2D6 | |
| SCHEMBL10904738 | 0.73 | NPSR1 (0.37) | ALDH1A1ALOX15HSD17B10LMNAKDM4E | |
| SCHEMBL1998499 | 0.73 | ACHE (0.44) | ALOX5PTGS2 | |
| SCHEMBL11108600 | 0.72 | GSTP1 (0.48) | CYP1A2CYP4F2CYP4A11BRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050191735-A1 | Oxidoreductase | IEP GMBH (DE) | 2005-09-01 | — | — | US | disclosed |